TrumpRx, the federal website for discounted drug prices, opened in February with 43 medications, priced from $3.15 for Medrol to $2,217 for Ngenla. CBS News reported on February 6, 2026 that the discounts are available only to patients paying cash: the site does not accept insurance, and money spent there does not count toward a deductible.
What the launch list charged
The 43 drugs and their cash prices, as listed at launch, ran across a wide range. Cytomel was $6, Diflucan $14.06, and Insulin Lispro $25. In the middle were Premarin at $99, Chantix at $106.20, Zyvox at $122.74, Farxiga at $181.59 and Pristiq at $200.10. Further up were Vfend at $306.98, Zavzpret at $594.84 and Viracept at $607.20. At the top were Xeljanz at $1,518 and Ngenla at $2,217.
The injectable and pill weight-loss brands sit near the middle of that range. The launch list showed Ozempic Pen at $199, Wegovy Pen at $199, Zepbound at $299 and a Wegovy Pill at $149. The TrumpRx site today lists the Wegovy pill at $149 a month under its “Lowest Presidential Deal” label, against an original price of $1,349 a month.
Is cash cheaper than the plan?
The question for anyone with a prescription plan is whether the cash price beats the copay. The answer is not the same for every drug. Kaye Pestaina, who directs the patient and consumer protections program at KFF, told CBS that TrumpRx is a place to check for cheaper direct-to-consumer prices, and said “It’s not a storefront.” She added that for most people, insurance is cheaper.
Dr. Mehmet Oz, the administrator of the Centers for Medicare & Medicaid Services, framed it as a comparison step when the site opened. “You should not be buying drugs anymore, going forward, without at least checking,” he said. Merith Basey, CEO of Patients for Affordable Drugs Now, told CBS that fertility drug pricing could help many people because those drugs usually are not covered by insurance.
A cash purchase on TrumpRx does not count toward a deductible, so a $149 pill or a $199 pen is paid in full from pocket. The Benefits Checklist scans 11 benefit programs, including Medicare Savings Programs and Extra Help, with the 2026 income limits for each, and several of those programs pay part of a drug bill.
Scan the Benefits Checklist for the 11 programs that pay part of a prescription bill →
How Medicare drug coverage prices the same fills
For people on Medicare, the comparison is against a Part D plan. Medicare.gov lists a 2027 out-of-pocket cap of $2,400, a maximum 2027 deductible of $700 and a 2027 base beneficiary premium of $41.33. A cash purchase made outside the plan does not count toward the deductible, per CBS, so a person who fills a monthly prescription at the TrumpRx price is spending money the deductible does not count.
The prices are a snapshot. CBS gave the launch roster and prices as of February, and the TrumpRx site is where the current figure sits.
The White House called the site a source of “immediate relief” for patients in a fact sheet, according to CBS. President Trump has also urged Congress to pass “The Great Healthcare Plan,” which the White House says would let health plans cover purchases made through TrumpRx. At launch, each price was a decision about out-of-pocket spending rather than a plan benefit.
The White House called the site a source of “immediate relief” for patients in a fact sheet, according to CBS. President Trump has also urged Congress to pass “The Great Healthcare Plan,” which the White House says would let health plans cover purchases made through TrumpRx. At launch, each price was a decision about out-of-pocket spending rather than a plan benefit.
Comparing a cash price with the plan copay before a refill
The free route is the TrumpRx site, where the current cash price for each drug is listed. Before the next refill, look up the exact drug and strength there, then call the pharmacy or the plan and ask what the same fill costs through insurance this month. Write both numbers down side by side.
Two things change the math. Cash spending on TrumpRx does not count toward a deductible, which matters for anyone still working through one. And a plan copay can drop once the deductible is met, while a cash price stays where it is.
Programs that pay part of a drug bill, such as Extra Help with Part D and Medicare Savings Programs, are separate from TrumpRx and must be applied for. CBS’s reporting and the TrumpRx listings are the source for every price in this story.
Wegovy at $149 cash, and no deductible credit
A $149-a-month cash price is paid entirely from pocket and does not move a deductible. The Benefits Checklist covers 11 benefit programs retirees most often miss, with the 2026 income limits and a 50-state phone directory, so the programs that pay part of a drug bill get a look before the cash price is accepted.
Check the Benefits Checklist’s 2026 income limits for drug-cost programs →
This article was produced with AI assistance and edited for accuracy against the sources linked above.
